Eric Topol

Founder and Director, Scripps Research Translational Institute (SRTI) | Bestselling Author, "Super Agers" and "Deep Medicine"
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Dr. Eric Topol is an internationally renowned physician-scientist known for his pioneering work using artificial intelligence, deep data, and genomics in the practice of individualized medicine. He is the Executive Vice President and a professor of molecular medicine at Scripps Research, the largest non-profit biomedical institute in the United States, and founder and director of the Scripps Research Translational Institute. One of the top 10 most cited researchers in medicine, he is also a practicing cardiologist.

As director of the Scripps Research Translational Institute, Dr. Eric Topol is leading the charge to revolutionize healthcare and radically improve human health through individualized medicine, which uses AI and genomic and digital data to tailor diagnosis, prevention, and treatment to the unique biological and social profile of the individual rather than to the “average” human of traditional medical science.
Prior to joining Scripps Research, Dr. Topol led the Cleveland Clinic to notoriety as the country’s #1 cardiac care center for 10 consecutive years and founded the clinic’s medical school, the Cleveland Clinic Lerner College of Medicine.

In addition to 30 medical textbooks, Dr. Topol has authored several bestselling books on the future of medicine, including, Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again, The Patient Will See You Now: The Future of Medicine is in Your Hands, and The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care.
To be published on May 6, 2025, his next book, Super Agers: An Evidence-based Approach to Longevity, extends from Dr. Topol's expertise at the intersection of technology and medicine. 'A detailed guide to a revolution transforming human longevity,' this highly anticipated book focuses on the medical breakthroughs that will increasingly enable healthy aging and ever-extending life spans: With medical forecasting, physicians can determine the conditions for which an individual patient is at the highest risk, and use this information to practice preventative, rather than reactive, medicine.
In both his books and his speeches, Dr. Topol helps the layperson and medical insiders alike understand the present and future of medicine, and the breakthrough moment in the history of human health care on which we are currently embarking. Having spent his career consistently on the cutting edge of progress in healthcare, he speaks on how AI can help us now, what our immediate future will bring in terms of faster data, and the moves we should make to reduce medical errors and balance the human and AI in medicine.
As the principal investigator to two National Institutes of Health (NIH) grants totaling hundreds of millions of dollars that make this work possible (the All of Us Research Program in support of precision medicine, and a Clinical and Translational Science Award that promotes innovation in medicine), Dr. Topol is uniquely positioned to explain the latest breakthroughs and why we should expect them to continue.
Dr. Topol is the Editor-in-Chief of Medscape, an informational resource for clinicians and medical scientists, and from 2019 to 2023 hosted the platform’s Medicine and the Machine podcast alongside fellow Leigh Bureau speaker Dr. Abraham Verghese.
His Substack Ground Truths boasts over 123,000 subscribers with a mission to deliver reliable scientific information in a growing sea of mis- and disinformation.
He was commissioned by Britain's Secretary of State for Health and Social Care to lead a review into how pioneering treatments and technologies can transform healthcare delivery through the National Health Service. Published in 2019 as The Topol Review: Preparing the Healthcare Workforce to deliver the digital future, the document continues to guide NHS England into the future of healthcare, along with The Topol Digital Fellowship, an NHS Digital Academy program that trains health and social care professionals to lead digital health transformations and innovations in their organizations.
‍Honors and Credentials
  • Named the #1 Most Influential Physician Executive in the United States, by Modern Healthcare Magazine
  • Awarded the Simon Dack Award from the American College of Cardiology
  • Awarded the Andreas Grüntzig Ethica Award from PCR
  • Awarded The Charles Force Hutchison and Marjorie Smith Hutchison Medal from the University of Rochester, the university's highest alumni honor.

Dr. Topol attended medical school at the University of Rochester before completing his residency in internal medicine at the University of California, San Francisco, and his fellowship in cardiovascular medicine at Johns Hopkins University.
He was elected to the National Academy of Medicine, the American Association of Physicians, the American Society of Clinical Investigation, and the Johns Hopkins Society of Scholars.

Topics

The Future of Medicine

Dr. Eric Topol has long had his eye turned to the future of medicine and has an impressive record of getting things right. His prescient bestselling books—The Creative Destruction of Medicine,The Patient Will See You Now, and Deep Medicine—each tackle an important merging of healthcare and technology that has since come to fruition. From the widespread usage of telemedicine, to increased patient autonomy and medical AI modeling, Topol seems to know what’s coming. In this evergreen presentation that captures the latest findings, Dr. Topol gives audiences a peek into his crystal ball to discover the innovations in life sciences, drug development, and technology that are poised to not only disrupt but truly enhance the healthcare space for patients and practitioners alike.

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Artificial Intelligence and Deep Medicine

The doctor-patient relationship has suffered due to the big business approach that values efficiency over humanity. Physicians, burned out from the added responsibility as data clerks thanks to electronic health records, spend less time with their patients and are often distracted in the few minutes they do share. Patients feel shortchanged and doctors are dismayed by not being able to deliver the level of care their patients deserve. Dr. Eric Topol refers to this development as shallow medicine. Counterintuitively, he believes artificial intelligence can make healthcare human again, repair the doctor-patient relationship, and free up the bandwidth to return to the practice of deep medicine. In this talk based on his bestselling book Deep Medicine, Dr. Topol discusses AI’s potential to revolutionize healthcare while addressing current limitations and areas of concern such as bias and privacy.

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Extending Our Healthspan: Living Well for Longer

Longevity is a hot topic these days but is making it to 100 years of age even desirable if it just equates to more years in pain, riddled with disease, spending most of our waking hours being poked and prodded through treatments? Thanks to the convergence of decades of biomedical and technological advances, soon we’ll be able to live healthier for longer. Whereas lifespan is the number of years we’re alive, healthspan considers the number of years we’re healthy and ailment-free. In this talk, Dr. Eric Topol explores the interplay of the five components of our healthspan extension toolkit—lifestyle, biological “omics” such as genomic sequencing and gut microbiomes, artificial intelligence, drugs and vaccines, and cell-based treatments—and the role each plays in giving us longer, healthier lives. While presenting the scientific breakthroughs that are adding more vibrant years onto our lives, the former anti-aging skeptic breaks down what we know, what remains unknown, and the bumps we’re likely to encounter along the way.

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High Performance Medicine

At the center of Dr. Eric Topol’s work is the mission to revolutionize healthcare and radically improve human health. The goal: high performance medicine and care; the approach: individualized medicine. Individualized medicine uses artificial intelligence and both genomic and digital data to tailor medical care to the unique biological, environmental, behavioral, and social profile of the individual patient rather than to the “average” human of traditional medical science. As the average human being does not exist, our current generalized approach to medicine is failing our patients in many important ways. In this talk, Dr. Eric Topol shares the latest advances in the mission to make high performance, individualized healthcare a common reality.

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Videos

Pradeep Natarajan: Preventing Heart Disease
Eric Topol
On A.I., Longevity and Being a Digital Human
Eric Topol
Geoffrey Hinton: Large Language Models in Medicine. They Understand and Have Empathy
Eric Topol
Can AI catch what doctors miss?
Eric Topol
How technology is reshaping the way cancer is diagnosed and treated | Washington Post Live
Eric Topol
Topol on using AI in ‘changing the fate of cancer’
Eric Topol
Straight Talk on A.I. Large Language Models
Eric Topol
The Impact of GPT-4 in Medicine | Ground Truths Podcast with Eric Topol and Peter Lee
Eric Topol
Deep Medicine: How Artificial Intelligence Can Make Health Care Human Again | Aspen Ideas Festival
Eric Topol
Preparing the healthcare workforce to deliver the digital future
Eric Topol
Is this the future of health? | The Economist
Eric Topol
Digital medical wireless devices and the future of medicine | TEDMed
Eric Topol
Big Data in Biomedicine
Eric Topol

Articles

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Joseph Allen: The Pivotal Importance of Air Quality, Ventilation and Exposures (Such as "Forever Chemicals") For Our Health
Ground Truths
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Medical forecasting
Science
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TIME100 Health: Eric Topol - Scientific Translator
TIME
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When Medical A.I. is Lifesaving
Ground Truths
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On A.I., Longevity and Being a Digital Human
Ground Truths
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A Big Week in Medical A.I.
Ground Truths | Substack
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Solving the puzzle of Long Covid
Science
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Toward the eradication of medical diagnostic errors
Science
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Opinion: The U.S. is facing the biggest COVID wave since Omicron. Why are we still playing make-believe?
Los Angeles Times
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Physicians: Shape Your AI Future or Someone Else Will
Medicine and the Machine
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As artificial intelligence goes multimodal, medical applications multiply
Science Magazine
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Medical A.I. is On a Tear, Part Two
Ground Truths
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Medical A.I. is on a tear - part one
Ground Truths
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The imperative for regulatory oversight of large language models (or generative AI) in healthcare
nature
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Scripps Research awarded $46.8 million by NIH to promote human health through innovative translational science and training
Scripps Research
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A.I for predicting high-risk pancreatic cancer
Ground Truths
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When Patient Questions Are Answered With Higher Quality and Empathy by ChatGPT than Physicians
Ground Truths
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Foundation models for generalist medical artificial intelligence
nature
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The GPT-x Revolution in Medicine
Ground Truths

Podcasts

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Artificial Intelligence
Patient-Centered Care
Disruption in Healthcare
Physicians & Other Providers
Technology Transforming Healthcare
Health Innovation
Improving Quality
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